Sulyman Barkho

An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with <i>In Vivo</i> Efficacy against Drug-Resistant Gram-Negative Infections

Erica N. Parker, Brett N. Cain, Behnoush Hajian et al. · ACS Central Science · 2022 · 76 citations · Full text

Life Sciences, Medicinal Chemistry, Microbiology +17

Structural characterisation of the catalytic domain of botulinum neurotoxin X - high activity and unique substrate specificity

Geoffrey Masuyer, Sicai Zhang, Sulyman Barkho et al. · Scientific Reports · 2018 · 42 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

High-Throughput Neutralization and Serology Assays Reveal Correlated but Highly Variable Humoral Immune Responses in a Large Population of Individuals Infected with SARS-CoV-2 in the US between March and August 2020

Shuting Zhang, Peijun Ma, Marek Orzechowski et al. · mBio · 2023 · 18 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Distal Loop Flexibility of a Regulatory Domain Modulates Dynamics and Activity of C-Terminal Src Kinase (Csk)

Sulyman Barkho, Levi Pierce, Maria L. McGlone et al. · PLoS Computational Biology · 2013 · 13 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Allosteric Switching of Agonist/Antagonist Activity by a Single Point Mutation in the Interluekin-1 Receptor Antagonist, IL-1Ra

Kendra L. Hailey, Dominique T. Capraro, Sulyman Barkho et al. · Journal of Molecular Biology · 2013 · 12 citations

Medicine, Medicinal Chemistry, Pharmacology +17