Concepedia

Ne Guo

NG

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Publications

5

Citations

127

H-Index

5

Active since

2017

Affiliations

Shanghai Institute of Materia Medica(Current)

University of Chinese Academy of Sciences

Chinese Academy of Sciences

Qingdao National Laboratory for Marine Science and Technology

Ne Guo is an author at Shanghai Institute of Materia Medica specializing in molecular oncology, oncology, and parp inhibition.

ORCID

Publications per year

2017–2023

5

Publications

5

Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance

Li‐Min Wang, Pingyuan Wang, Hui Yang et al. · EMBO Molecular Medicine · 2023 · 44 citations · Full text

, , +16

Increased PARP1‐DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1‐DNA trapping is correlated with PARP1 inhibitor's cytotoxicity

Huadong Chen, Chuan‐Huizi Chen, Yuting Wang et al. · International Journal of Cancer · 2019 · 38 citations · Full text

, , +16

Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy

Wen‐Hua Chen, Ne Guo, Ming‐Hui Qi et al. · European Journal of Medicinal Chemistry · 2017 · 24 citations · Full text

, , +7

Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion

Ne Guo, Mengzhu Li, Limin Wang et al. · Cancer Biology & Therapy · 2022 · 11 citations · Full text

, , +17

Novel mutations in <i>BRCA2</i> intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors.

Huadong Chen, Ne Guo, Shanshan Song et al. · PubMed · 2020 · 10 citations · Full text

, , +15

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