Chuan‐Huizi Chen

YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer

Dewei Jiang, Ting Qiu, Junjiang Peng et al. · Cell Death and Differentiation · 2022 · 85 citations · Full text

Medicine, Molecular Biology, Oncology +12

Inhibition of super enhancer downregulates the expression of KLF5 in basal-like breast cancers

Chuan‐Huizi Chen, Nong Yang, Yongchang Zhang et al. · International Journal of Biological Sciences · 2019 · 45 citations · Full text

Medicine, Molecular Biology, Oncology +13

Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent <i>in vitro</i> and <i>in vivo</i> anticancer activity, characteristic of high tissue distribution

Jin‐Xue He, Meng Wang, Xia‐Juan Huan et al. · Oncotarget · 2016 · 41 citations · Full text

Life Sciences, Oncology, Pharmacology +16

Increased PARP1‐DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1‐DNA trapping is correlated with PARP1 inhibitor's cytotoxicity

Huadong Chen, Chuan‐Huizi Chen, Yuting Wang et al. · International Journal of Cancer · 2019 · 38 citations · Full text

Medicine, Molecular Biology, Oncology +16

KLF5-induced lncRNA IGFL2-AS1 promotes basal-like breast cancer cell growth and survival by upregulating the expression of IGFL1

Haixia Wang, Yujie Shi, Chuan‐Huizi Chen et al. · Cancer Letters · 2021 · 35 citations

Medicine, Molecular Biology, Oncology +10