Shady Saad

Reversible protein aggregation is a protective mechanism to ensure cell cycle restart after stress

Shady Saad, Gea Cereghetti, Yuehan Feng et al. · Nature Cell Biology · 2017 · 202 citations

Life Sciences, Cell Biology, Molecular Biology +16

Cytosolic pH Regulates Cell Growth through Distinct GTPases, Arf1 and Gtr1, to Promote Ras/PKA and TORC1 Activity

Reinhard Dechant, Shady Saad, Alfredo J. Ibáñez et al. · Molecular Cell · 2014 · 148 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly

Gea Cereghetti, Caroline Wilson-Zbinden, Vera M. Kissling et al. · Nature Cell Biology · 2021 · 62 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

A hydrophobic low-complexity region regulates aggregation of the yeast pyruvate kinase Cdc19 into amyloid-like aggregates in vitro

Erica Grignaschi, Gea Cereghetti, Fulvio Grigolato et al. · Journal of Biological Chemistry · 2018 · 35 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

DNA binding and mitotic phosphorylation protect polyglutamine proteins from assembly formation

Shady Saad, Tomek Swigut, Saman Tabatabaee et al. · Cell · 2025 · 15 citations · Full text

Life Sciences, Genetics, Molecular Biology +17