Peter H.G.M. Willems

mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

Shih‐Chin Cheng, Jessica Quintin, Robert A. Cramer et al. · Science · 2014 · 2.1K citations · Full text

Microbial Pathogens, Trained Immunity, Innate Immune System +25

Molecular Identification of the Apical Ca2+Channel in 1,25-Dihydroxyvitamin D3-responsive Epithelia

Joost G.J. Hoenderop, Annemiete W.C.M. van der Kemp, Anita Hartog et al. · Journal of Biological Chemistry · 1999 · 596 citations · Full text

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

Shih‐Chin Cheng, Brendon P. Scicluna, Rob J.W. Arts et al. · Nature Immunology · 2016 · 587 citations

Inflammation, Energy Metabolism, Granulocyte +11

Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells

Farhan Basit, Lisanne MPE van Oppen, Laura Schöckel et al. · Cell Death and Disease · 2017 · 551 citations · Full text

Mitochondrial function and morphology are impaired in <i>parkin</i>‐mutant fibroblasts

Heather Mortiboys, Kelly Jean Thomas Craig, Werner J.H. Koopman et al. · Annals of Neurology · 2008 · 345 citations · Full text