Werner J.H. Koopman

Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells

Farhan Basit, Lisanne MPE van Oppen, Laura Schöckel et al. · Cell Death and Disease · 2017 · 551 citations · Full text

Mitochondrial function and morphology are impaired in <i>parkin</i>‐mutant fibroblasts

Heather Mortiboys, Kelly Jean Thomas Craig, Werner J.H. Koopman et al. · Annals of Neurology · 2008 · 345 citations · Full text

Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells

Martina Bajzíková, Jaromíra Kovářová, Ana R. Coelho et al. · Cell Metabolism · 2018 · 299 citations · Full text

Biochemistry, Oncogenic Agent, Respiration-deficient Cancer Cells +9

Inhibition of complex I of the electron transport chain causes O₂⁻·-mediated mitochondrial outgrowth

Werner J.H. Koopman, Sjoerd Verkaart, Henk-Jan Visch et al. · American Journal of Physiology-Cell Physiology · 2005 · 291 citations · Full text

An anaerobic mitochondrion that produces hydrogen

Brigitte Boxma, Rob M. de Graaf, Georg W.M. van der Staay et al. · Nature · 2005 · 251 citations · Full text

Biology, Anaerobic Mitochondrion, Biosynthesis +9