Pardeep Heir

Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis

Severa Bunda, Kelly Burrell, Pardeep Heir et al. · Nature Communications · 2015 · 228 citations · Full text

Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor–mediated upregulation of caveolin-1

Yi Wang, O. Roche, Chaoying Xu et al. · Proceedings of the National Academy of Sciences · 2012 · 141 citations · Full text

Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation

Severa Bunda, Pardeep Heir, Tharan Srikumar et al. · Proceedings of the National Academy of Sciences · 2014 · 101 citations · Full text

Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia

Ryan C. Russell, Roxana I. Sufan, Bing Zhou et al. · Nature Medicine · 2011 · 80 citations

Transcriptional Regulation, Signal Transduction, Cell Regulation +8

CIC protein instability contributes to tumorigenesis in glioblastoma

Severa Bunda, Pardeep Heir, Julie Metcalf et al. · Nature Communications · 2019 · 78 citations · Full text