What Contributes to Serotonin–Norepinephrine Reuptake Inhibitors’ Dual-Targeting Mechanism? The Key Role of Transmembrane Domain 6 in Human Serotonin and Norepinephrine Transporters Revealed by Molecular Dynamics Simulation

Weiwei Xue, Fengyuan Yang, Panpan Wang, +3

ACS Chemical Neuroscience

Computational identification of the binding mechanism of a triple reuptake inhibitor amitifadine for the treatment of major depressive disorder

Weiwei Xue, Panpan Wang, Gao Tu, +6

Physical Chemistry Chemical Physics

Drug TargetPharmacotherapySystem PharmacologyOnly DrugPharmacodynamic Modeling +24

Identification of the inhibitory mechanism of FDA approved selective serotonin reuptake inhibitors: an insight from molecular dynamics simulation study

Weiwei Xue, Panpan Wang, Bo Li, +7

Physical Chemistry Chemical Physics

The Human Kinome Targeted by FDA Approved Multi-Target Drugs and Combination Products: A Comparative Study from the Drug-Target Interaction Network Perspective

Yinghong Li, Panpan Wang, Xiao Xu Li, +6

PLoS ONE

Drug TargetEngineeringMolecular BiologyPharmacotherapyHuman Kinome +17

Differentiating Physicochemical Properties between Addictive and Nonaddictive ADHD Drugs Revealed by Molecular Dynamics Simulation Studies

Panpan Wang, Xiaoyu Zhang, Tingting Fu, +5

ACS Chemical Neuroscience

PsychopharmacologyMolecular DynamicsSocial SciencesAdhd DrugsBiophysics +15

Differentiating physicochemical properties between NDRIs and sNRIs clinically important for the treatment of ADHD

Panpan Wang, Tingting Fu, Xiaoyu Zhang, +5

Biochimica et Biophysica Acta (BBA) - General Subjects

AdhdNeuropsychologyPsychiatryNeurological DisorderNeuropharmacology +6

Opioid-associated iatrogenic withdrawal in critically ill adult patients: a multicenter prospective observational study

Panpan Wang, Elaine Huang, Xue Feng, +10

Annals of Intensive Care

Exploring the Inhibitory Mechanism of Approved Selective Norepinephrine Reuptake Inhibitors and Reboxetine Enantiomers by Molecular Dynamics Study

Guoxun Zheng, Weiwei Xue, Panpan Wang, +6

Scientific Reports

Comparison of FDA Approved Kinase Targets to Clinical Trial Ones: Insights from Their System Profiles and Drug-Target Interaction Networks

Jingyu Xu, Panpan Wang, Hong Yang, +7

BioMed Research International

Drug TargetOncologyInteractomicsMedicineRational Drug Design +12

Effectiveness of a Therapeutic Summer Camp for Children With ADHD

Julie Hantson, Panpan Wang, Michael Grizenko-Vida, +4

Journal of Attention Disorders