Nicholas J Fraser

Evolution of Protein Quaternary Structure in Response to Selective Pressure for Increased Thermostability

Nicholas J Fraser, Jianwei Liu, Peter D. Mabbitt et al. · Journal of Molecular Biology · 2016 · 53 citations · Full text

Protein Chemistry, Protein Assembly, Protein Folding +9

Molecular basis for the behavioral effects of the odorant degrading enzyme Esterase 6 in Drosophila

Faisal Younus, Nicholas J Fraser, Chris W. Coppin et al. · Scientific Reports · 2017 · 45 citations · Full text

Structure of an Insecticide Sequestering Carboxylesterase from the Disease Vector <i>Culex quinquefasciatus:</i> What Makes an Enzyme a Good Insecticide Sponge?

Davis H. Hopkins, Nicholas J Fraser, Peter D. Mabbitt et al. · Biochemistry · 2017 · 36 citations

Evolutionary Expansion of the Amidohydrolase Superfamily in Bacteria in Response to the Synthetic Compounds Molinate and Diuron

Elena Sugrue, Nicholas J Fraser, Davis H. Hopkins et al. · Applied and Environmental Microbiology · 2015 · 35 citations · Full text

Bioorganic Chemistry, Engineering, Aldo-keto Reductase +20

Conformational Disorganization within the Active Site of a Recently Evolved Organophosphate Hydrolase Limits Its Catalytic Efficiency

Peter D. Mabbitt, G.J. Correy, Tamara Meirelles et al. · Biochemistry · 2016 · 25 citations · Full text

Crystal Structure, Biochemistry, Protein Folding +15