S Hubele

Activated human T cells express a ligand for the human B cell‐associated antigen CD40 which participates in T cell‐dependent activation of B lymphocytes

Peter J. L. Lane, André Traunecker, S Hubele et al. · European Journal of Immunology · 1992 · 316 citations

Adaptive Immune System, Immunology, Immune Regulation +19

Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation.

Peter J. L. Lane, Thomas Brocker, S Hubele et al. · The Journal of Experimental Medicine · 1993 · 252 citations · Full text

Adaptive Immune System, Mouse B Cells, Immunology +18

B cell function in mice transgenic for mCTLA4-H gamma 1: lack of germinal centers correlated with poor affinity maturation and class switching despite normal priming of CD4+ T cells.

Peter J. L. Lane, Corinne Burdet, S Hubele et al. · The Journal of Experimental Medicine · 1994 · 132 citations · Full text

Lymphocyte Development, Genetics, T-regulatory Cell +19

Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4+ T cells and defective antibody production in vivo.

Franca Ronchese, Barbara Hausmann, S Hubele et al. · The Journal of Experimental Medicine · 1994 · 128 citations · Full text

Mctla4-h Gamma 1, Autoimmune Disease, Allergy +14

Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human gamma 1.

Peter J. L. Lane, Walter Gerhard, S Hubele et al. · PubMed · 1993 · 93 citations · Full text

Molecular Regulation, T-regulatory Cell, Immunology +19