Cyrus M. Lacbay

Unraveling the Prenylation–Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors

Cyrus M. Lacbay, Daniel D. Waller, Jaeok Park et al. · Journal of Medicinal Chemistry · 2018 · 43 citations · Full text

Hematological Malignancy, Prenylation–cancer Paradox, Oncology +15

Modular Assembly of Purine-like Bisphosphonates as Inhibitors of HIV-1 Reverse Transcriptase

Cyrus M. Lacbay, John Mancuso, Yih‐Shyan Lin et al. · Journal of Medicinal Chemistry · 2014 · 41 citations · Full text

Modular Assembly, Molecular Biology, Antiviral Drug +17

Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase

Jaeok Park, Chun Yuen Leung, Alexios N. Matralis et al. · Journal of Medicinal Chemistry · 2017 · 27 citations · Full text

Thienopyrimidine-based Monophosphonate, Medicinal Chemistry, Pharmaceutical Chemistry +15

Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500)

W. Cameron Black, Abbas Abdoli, Xiuli An et al. · Journal of Medicinal Chemistry · 2024 · 21 citations · Full text

Drug Target, Immunology, Pharmacotherapy +21

Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase

Dimitrios Gritzalis, Jaeok Park, Wei Chiu et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 19 citations · Full text

Biochemistry, Medicine, Natural Sciences +10