Ding Du

Discovery of 4-((3′<i>R</i>,4′<i>S</i>,5′<i>R</i>)-6″-Chloro-4′-(3-chloro-2-fluorophenyl)-1′-ethyl-2″-oxodispiro[cyclohexane-1,2′-pyrrolidine-3′,3″-indoline]-5′-carboxamido)bicyclo[2.2.2]octane-1-carboxylic Acid (AA-115/APG-115): A Potent and Orally Active Murine Double Minute 2 (MDM2) Inhibitor in Clinical Development

Angelo Aguilar, Jianfeng Lü, Liu Liu et al. · Journal of Medicinal Chemistry · 2017 · 203 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

1,4-Alkylcarbonylation of 1,3-Enynes to Access Tetra-Substituted Allenyl Ketones <i>via</i> an NHC-Catalyzed Radical Relay

Lei Chen, Lin Chen, Simiao Zhang et al. · ACS Catalysis · 2021 · 106 citations

Natural Sciences, Chemistry, Catalysis +14

Synthesis and Biological Activities of Novel Pyrazole Oxime Derivatives Containing a 2-Chloro-5-thiazolyl Moiety

Hong Dai, Yongqiang Li, Ding Du et al. · Journal of Agricultural and Food Chemistry · 2008 · 94 citations

Pharmacy, Entomology, Medicinal Chemistry +13

N-Heterocyclic Carbene-Catalyzed Three-Component Domino Reaction of Alkynyl Aldehydes with Oxindoles

Ding Du, Zhongyuan Hu, Jianlin Jin et al. · Organic Letters · 2012 · 91 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

Synthesis of TiO₂/Bi₂MoO₆ Composite for Partial Oxidation of Aromatic Alkanes under Visible-Light Illumination

Luna Song, Feng Ding, Yakun Yang et al. · ACS Sustainable Chemistry & Engineering · 2018 · 88 citations

Natural Sciences, Materials Engineering, Materials Science +17