Mattia Conte

Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation

Naoki Kubo, Haruhiko Ishii, Xiong Xiong et al. · Nature Structural & Molecular Biology · 2021 · 294 citations · Full text

Transcriptional Regulation, Genetics, Gene Regulation +5

CTCF mediates dosage- and sequence-context-dependent transcriptional insulation by forming local chromatin domains

Hui Huang, Quan Zhu, Adam Jussila et al. · Nature Genetics · 2021 · 189 citations · Full text

Chromatin, Transcriptional Regulation, Local Chromatin Domains +14

Polymer physics indicates chromatin folding variability across single-cells results from state degeneracy in phase separation

Mattia Conte, Luca Fiorillo, Simona Bianco et al. · Nature Communications · 2020 · 148 citations · Full text

Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding

Mattia Conte, Ehsan Irani, Andrea M. Chiariello et al. · Nature Communications · 2022 · 98 citations · Full text

Comparison of the Hi-C, GAM and SPRITE methods using polymer models of chromatin

Luca Fiorillo, Francesco Musella, Mattia Conte et al. · Nature Methods · 2021 · 68 citations · Full text