Philip Hanoian

Probing the Electrostatics of Active Site Microenvironments along the Catalytic Cycle for <i>Escherichia coli</i> Dihydrofolate Reductase

C. Tony Liu, Joshua P. Layfield, Robert Stewart et al. · Journal of the American Chemical Society · 2014 · 98 citations · Full text

Functional significance of evolving protein sequence in dihydrofolate reductase from bacteria to humans

C. Tony Liu, Philip Hanoian, Jarrod B. French et al. · Proceedings of the National Academy of Sciences · 2013 · 94 citations · Full text

Enhancing transcription–replication conflict targets ecDNA-positive cancers

Jun Tang, Natasha E. Weiser, Guiping Wang et al. · Nature · 2024 · 67 citations · Full text

Hydrogen Bonding in the Active Site of Ketosteroid Isomerase: Electronic Inductive Effects and Hydrogen Bond Coupling

Philip Hanoian, Paul A. Sigala, Daniel Herschlag et al. · Biochemistry · 2010 · 39 citations

Hydrogen Bond Coupling, Engineering, Biochemistry +13

Experimental and Computational Mutagenesis To Investigate the Positioning of a General Base within an Enzyme Active Site

Jason P. Schwans, Philip Hanoian, Benjamin J. Lengerich et al. · Biochemistry · 2014 · 21 citations

Enzyme Active Site, Cellular Enzymology, Protein Assembly +15