Jans Alzate‐Morales

Selective Interaction of Lansoprazole and Astemizole with Tau Polymers: Potential New Clinical Use in Diagnosis of Alzheimer's Disease

Leonel E. Rojo, Jans Alzate‐Morales, Iván Saavedra et al. · Journal of Alzheimer s Disease · 2010 · 139 citations · Full text

Engineering, Tau Polymers, Neurochemical Biomarkers +18

Performance of the MM/GBSA scoring using a binding site hydrogen bond network-based frame selection: the protein kinase case

Francisco Adasme‐Carreño, Camila Muñoz‐Gutierrez, Julio Caballero et al. · Physical Chemistry Chemical Physics · 2014 · 76 citations · Full text

Insights into the Structural Basis of N2 and O6 Substituted Guanine Derivatives as Cyclin-Dependent Kinase 2 (CDK2) Inhibitors: Prediction of the Binding Modes and Potency of the inhibitors by Docking and ONIOM Calculations

Jans Alzate‐Morales, Julio Caballero, Ariela Vergara‐Jaque et al. · Journal of Chemical Information and Modeling · 2009 · 59 citations

Novel <i>N</i>‐allyl/propargyl tetrahydroquinolines: Synthesis via Three‐component Cationic Imino Diels–Alder Reaction, Binding Prediction, and Evaluation as Cholinesterase Inhibitors

Yeray A. Rodríguez‐Núñez, Margarita Gutiérrez, David Ramírez et al. · Chemical Biology & Drug Design · 2016 · 59 citations · Full text

A Computational Study of the Protein-Ligand Interactions in CDK2 Inhibitors: Using Quantum Mechanics/Molecular Mechanics Interaction Energy as a Predictor of the Biological Activity

Jans Alzate‐Morales, Renato Contreras, Alejandro Soriano et al. · Biophysical Journal · 2006 · 54 citations · Full text

Biological Activity, Engineering, Medicine +13