Donna Pruess-Schwartz

Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons.

Tsutomu Shimada, Martin Mv, Donna Pruess-Schwartz et al. · PubMed · 1989 · 222 citations

Pharmacy, Biochemistry, Toxicology +15

Reactivity and Tumorigenicity of Bay-Region Diol Epoxides Derived from Polycyclic Aromatic Hydrocarbons

D. M. JERINA, Jane M. Sayer, Shiv Kumar Agarwal et al. · Advances in experimental medicine and biology · 1986 · 60 citations

Medicine, Oncology, Toxicology +14

Peroxyl radical- and cytochrome P-450-dependent metabolic activation of (+)-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene in mouse skin in vitro and in vivo.

Donna Pruess-Schwartz, A Nimesheim, L.J. Marnett · PubMed · 1989 · 37 citations

Pharmacy, Biochemistry, Toxicology +11

Stereochemical specificity in the metabolic activation of benzo(c)phenanthrene to metabolites that covalently bind to DNA in rodent embryo cell cultures.

Donna Pruess-Schwartz, William M. Baird, Haruhiko Yagi et al. · PubMed · 1987 · 33 citations

Medicine, Biochemistry, Toxicology +17

Species- and length of exposure-dependent differences in the benzo(a)pyrene:DNA adducts formed in embryo cell cultures from mice, rats, and hamsters.

Saı̈d Sebti, Donna Pruess-Schwartz, William M. Baird · PubMed · 1985 · 28 citations

Pharmacy, Toxicology, Biochemical Toxicology +10