A Pyrazole Derivative, YM-58483, Potently Inhibits Store-Operated Sustained Ca2+ Influx and IL-2 Production in T Lymphocytes

Jun Ishikawa, Keiko Ohga, Taiji Yoshino, +4

The Journal of Immunology

T-regulatory CellImmunologyPyrazole DerivativeImmunologic MechanismImmunotherapy +17

YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models

Taiji Yoshino, Jun Ishikawa, Keiko Ohga, +6

European Journal of Pharmacology

AsthmaAllergyLung InflammationMedicineImmunology +6

The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo

Keiko Ohga, Ryuichi Takezawa, Taiji Yoshino, +3

Pulmonary Pharmacology & Therapeutics

InflammationAsthmaAirway ResponsesInflammatory Lung DiseaseLung Inflammation +9

Effect of celecoxib, a cyclooxygenase-2 inhibitor, on the pathophysiology of adjuvant arthritis in rat

Masahiro Noguchi, Aishi Kimoto, Seiji Kobayashi, +3

European Journal of Pharmacology

InflammationRheumatologyRheumatoid DisorderAnti-inflammatoryMedicine +8

Pharmacological Profile of Celecoxib, a Specific Cyclooxygenase-2 Inhibitor

Taiji Yoshino, Aishi Kimoto, Seiji Kobayashi, +5

Arzneimittelforschung

Effects of solifenacin succinate (YM905) on detrusor overactivity in conscious cerebral infarcted rats

Masanori Suzuki, Akiyoshi Ohtake, Taiji Yoshino, +7

European Journal of Pharmacology

MedicineNeuropharmacologyDetrusor OveractivityNeuroprotectionNeuroscience +6

Novel potent and selective Ca2+ release-activated Ca2+ (CRAC) channel inhibitors. Part 3: Synthesis and CRAC channel inhibitory activity of 4′-[(trifluoromethyl)pyrazol-1-yl]carboxanilides

Yasuhiro Yonetoku, Hirokazu Kubota, Yoji Miyazaki, +7

Bioorganic & Medicinal Chemistry

Channel InhibitorsMolecular PharmacologyMedicinal ChemistryBiochemistryMedicine +6

Inhibitory effects of YM175, a bisphosphonate, on the progression of experimental periodontitis in beagle dogs

Naoto O'uchi, H. Nishikawa, Taiji Yoshino, +9

Journal of Periodontal Research

Participation of endogenous endothelin and ETA receptor in premicturition contractions in rats with bladder outlet obstruction

Masashi Ukai, Hironori Yuyama, Yukiko Noguchi, +8

Naunyn-Schmiedeberg s Archives of Pharmacology

Eta ReceptorPremicturition ContractionsPhysiologyEndogenous EndothelinCentral Nervous System +2

Study on Physiological Roles of Stimulation of Prostaglandin <scp>E₂</scp> Receptor Subtype <scp>EP2</scp> in Urethral Function in Rats

Ryoko Kurihara, Kenichiro Ishizu, Hajime Takamatsu, +2

LUTS Lower Urinary Tract Symptoms