Ryuichi Takezawa

A Pyrazole Derivative, YM-58483, Potently Inhibits Store-Operated Sustained Ca2+ Influx and IL-2 Production in T Lymphocytes

Jun Ishikawa, Keiko Ohga, Taiji Yoshino et al. · The Journal of Immunology · 2003 · 254 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain

Ryuichi Takezawa, Carsten Schmitz, Philippe Demeuse et al. · Proceedings of the National Academy of Sciences · 2004 · 183 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

A Pyrazole Derivative Potently Inhibits Lymphocyte Ca2+ Influx and Cytokine Production by Facilitating Transient Receptor Potential Melastatin 4 Channel Activity

Ryuichi Takezawa, Henrique Cheng, Andreas Beck et al. · Molecular Pharmacology · 2006 · 153 citations

Life Sciences, Immunology, Pharmacology +15

YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models

Taiji Yoshino, Jun Ishikawa, Keiko Ohga et al. · European Journal of Pharmacology · 2007 · 77 citations

Medicine, Immunology, Pharmacology +16

Characterization of YM-58483/BTP2, a novel store-operated Ca2+ entry blocker, on T cell-mediated immune responses in vivo

Keiko Ohga, Ryuichi Takezawa, Yasuhito Arakida et al. · International Immunopharmacology · 2008 · 76 citations

Life Sciences, Immunology, Pharmacology +14