Guanjing Chen

Small-molecule WNK inhibition regulates cardiovascular and renal function

Ken Yamada, Hyi-Man Park, Dean F. Rigel et al. · Nature Chemical Biology · 2016 · 162 citations · Full text

Molecular Physiology, Kidney Research, Medicine +8

Structure-Guided Design of Potent and Selective Pyrimidylpyrrole Inhibitors of Extracellular Signal-Regulated Kinase (ERK) Using Conformational Control

Alex M. Aronov, Qing Tang, Gabriel Martínez-Botella et al. · Journal of Medicinal Chemistry · 2009 · 144 citations · Full text

Drug Target, Chemical Biology, Tumor Biology +17

Flipped Out:  Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors

Alex M. Aronov, Christopher Baker, Guy W. Bemis et al. · Journal of Medicinal Chemistry · 2007 · 118 citations · Full text

Medicinal Chemistry, Drug Target, Medicine +12

Kinetic Mechanism of the p38-α MAP Kinase:  Phosphoryl Transfer to Synthetic Peptides

Guanjing Chen, Margaret Porter, John R. Bristol et al. · Biochemistry · 2000 · 54 citations

Molecular Biology, Synthetic Peptides, Peptide Science +19

Identification of a PCSK9-LDLR disruptor peptide with in vivo function

Margaret E. Brousseau, Kevin B. Clairmont, Glen Spraggon et al. · Cell chemical biology · 2021 · 42 citations

Inflammation, Signal Transduction, Peptide Library +7