Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

Volker Teichgräber, Martina Ulrich, Nicole Endlich, +13

Nature Medicine

InflammationFibrosisInflammatory Lung DiseaseImmunologyCell Death +5

Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide

Anne Gulbins, Fabian Schumacher, Katrin Anne Becker, +11

Molecular Psychiatry

Psychotropic MedicationPsychopharmacologyCell DeathSphingomyelin AccumulationPharmacotherapy +18

Rhinoviruses Infect Human Epithelial Cells via Ceramide-enriched Membrane Platforms

Heike Grassmé, Andrea Riehle, Barbara Wilker, +1

Journal of Biological Chemistry

Proteinlipid InteractionCell MembranePathogenesisViral PathogenesisImmunology +9

Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes

Ildikò Szabó, Jürgen Bock, Heike Grassmé, +5

Proceedings of the National Academy of Sciences

Molecular PhysiologySignal TransductionMitochondrial FunctionBax-induced ApoptosisApoptosis +11

Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells

Alexander Carpinteiro, Michael J. Edwards, Markus Hoffmann, +24

Cell Reports Medicine

Ceramide, membrane rafts and infections

Erich Gulbins, Stephan Dreschers, Barbara Wilker, +1

Journal of Molecular Medicine

AntibioticsPathogenesisKlebsiella PneumoniaePathologyMembrane Rafts +5

<i>Pseudomonas aeruginosa</i> Pyocyanin Induces Neutrophil Death <i>via</i> Mitochondrial Reactive Oxygen Species and Mitochondrial Acid Sphingomyelinase

Antonella Managò, Katrin Anne Becker, Alexander Carpinteiro, +7

Antioxidants and Redox Signaling

Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis

Huiming Peng, Li Cao, Stephanie Kadow, +12

Journal of Molecular Medicine

Staphylococcus aureus Alpha-Toxin Disrupts Endothelial-Cell Tight Junctions via Acid Sphingomyelinase and Ceramide

Katrin Anne Becker, Björn Fahsel, Hannes Kemper, +13

Infection and Immunity

Infections with Human Rhinovirus Induce the Formation of Distinct Functional Membrane Domains

Stephan Dreschers, Peter Franz, Claudia A. Dumitru, +3

Cellular Physiology and Biochemistry

Proteinlipid InteractionViral PathogenesisImmunologyViral Structural ProteinVirus Structure +14