Alexander F. J. van Aken

A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse

Christian Grimm, Math P. Cuajungco, Alexander F. J. van Aken et al. · Proceedings of the National Academy of Sciences · 2007 · 166 citations · Full text

Molecular Regulation, Genetics, Cellular Physiology +16

Mutations in Protocadherin 15 and Cadherin 23 Affect Tip Links and Mechanotransduction in Mammalian Sensory Hair Cells

Kumar N. Alagramam, Richard J. Goodyear, Ruishuang Geng et al. · PLoS ONE · 2011 · 138 citations · Full text

Harmonin-b, an actin-binding scaffold protein, is involved in the adaptation of mechanoelectrical transduction by sensory hair cells

Nicolas Michalski, Vincent Michel, Elisa Caberlotto et al. · Pflügers Archiv - European Journal of Physiology · 2009 · 86 citations · Full text

TRPML3 mutations cause impaired mechano‐electrical transduction and depolarization by an inward‐rectifier cation current in auditory hair cells of varitint‐waddler mice

Alexander F. J. van Aken, Margaret Atiba‐Davies, Walter Marcotti et al. · The Journal of Physiology · 2008 · 66 citations · Full text

Synaptic Transmission, Trpml3 Mutations, Mutant Trpml3 +23