Yuichi Koga

Discovery of Canagliflozin, a Novel <i>C</i>-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus

Sumihiro Nomura, Shigeki Sakamaki, Mitsuya Hongu et al. · Journal of Medicinal Chemistry · 2010 · 371 citations · Full text

Heteroaromatic Ring, Metabolic Syndrome, Medicinal Chemistry +15

Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cells

Anderson Miyoshi, Yoshihiko Kitajima, Kazuya Sumi et al. · British Journal of Cancer · 2004 · 279 citations · Full text

Palladium-catalyzed asymmetric arylation of 4,7-dihydro-1,3-dioxepin. Catalytic asymmetric synthesis of γ-butyrolactone derivatives

Yuichi Koga, Mikiko Sodeoka, Masakatsu Shibasaki · Tetrahedron Letters · 1994 · 68 citations

Catalytic Asymmetric Synthesis, Derivatives, Engineering +9

Methylation-induced silencing of ASC and the effect of expressed ASC on p53-mediated chemosensitivity in colorectal cancer

Takao Ohtsuka, Liu Xf, Yuichi Koga et al. · Oncogene · 2005 · 36 citations

Cancer Research, Oncogenic Agent, Medicine +10

C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors

Yuichi Koga, Shigeki Sakamaki, Mitsuya Hongu et al. · Bioorganic & Medicinal Chemistry · 2013 · 29 citations · Full text

Molecular Pharmacology, Heteroaryl Thiophene, Biochemistry +8