John F. Penrose

Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma.

Andrew S. Cowburn, Jerzy Soja, L. Adamek et al. · Journal of Clinical Investigation · 1998 · 552 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4.

B Lam, John F. Penrose, Gordon J. Freeman et al. · Proceedings of the National Academy of Sciences · 1994 · 297 citations

Life Sciences, Biochemistry, Molecular Biology +12

Eosinophil Lipid Bodies: Specific, Inducible Intracellular Sites for Enhanced Eicosanoid Formation

Patrı́cia T. Bozza, Wengui Yu, John F. Penrose et al. · The Journal of Experimental Medicine · 1997 · 216 citations · Full text

Life Sciences, Cell Biology, Immunology +17

T Helper Cell Type 2 Cytokines Coordinately Regulate Immunoglobulin E–Dependent Cysteinyl Leukotriene Production by Human Cord Blood–Derived Mast Cells

Fred H. Hsieh, Bing Lam, John F. Penrose et al. · The Journal of Experimental Medicine · 2001 · 214 citations · Full text

Life Sciences, Immunology, Hypersensitivity +16

5′ Flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States

Rachel Van Sambeek, Donald D. Stevenson, Mathew H. Baldasaro et al. · Journal of Allergy and Clinical Immunology · 2000 · 172 citations · Full text

Life Sciences, Genetics, Molecular Genetics +6