O. Jameel Shah

Inappropriate Activation of the TSC/Rheb/mTOR/S6K Cassette Induces IRS1/2 Depletion, Insulin Resistance, and Cell Survival Deficiencies

O. Jameel Shah, Zhiyong Wang, Tony Hunter · Current Biology · 2004 · 786 citations · Full text

Insulin Resistance, Metabolic Syndrome, Insulin Signaling +11

Turnover of the Active Fraction of IRS1 Involves Raptor-mTOR- and S6K1-Dependent Serine Phosphorylation in Cell Culture Models of Tuberous Sclerosis

O. Jameel Shah, Tony Hunter · Molecular and Cellular Biology · 2006 · 177 citations · Full text

Insulin Receptor, Cellular Physiology, Insulin Signaling +16

Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition

En-Kun Han, Thomas McGonigal, O. Jameel Shah et al. · Oncogene · 2007 · 169 citations

Molecular Pharmacology, Signal Transduction, Molecular Physiology +8

Acute attenuation of translation initiation and protein synthesis by glucocorticoids in skeletal muscle

O. Jameel Shah, Scot R. Kimball, Leonard S. Jefferson · American Journal of Physiology-Endocrinology and Metabolism · 2000 · 125 citations

Among translational effectors, p70S6k is uniquely sensitive to inhibition by glucocorticoids

O. Jameel Shah, Scot R. Kimball, Leonard S. Jefferson · Biochemical Journal · 2000 · 71 citations · Full text