Temporal and Spatial Analysis of Clinical and Molecular Parameters in Dextran Sodium Sulfate Induced Colitis

Yutao Yan, Vasantha L. Kolachala, Guillaume Dalmasso, +4

PLoS ONE

Dextran Sodium Sulfate (DSS) Induces Colitis in Mice by Forming Nano-Lipocomplexes with Medium-Chain-Length Fatty Acids in the Colon

Hamed Laroui, Sarah Ingersoll, Hong Chun Liu, +7

PLoS ONE

Drug-Loaded Nanoparticles Targeted to the Colon With Polysaccharide Hydrogel Reduce Colitis in a Mouse Model

Hamed Laroui, Guillaume Dalmasso, Hang Thi Thu Nguyen, +3

Gastroenterology

Biopolymer GelNanomedicineHydrogelsEngineeringDrug-loaded Nanoparticles Targeted +7

Nanoparticles With Surface Antibody Against CD98 and Carrying CD98 Small Interfering RNA Reduce Colitis in Mice

Bo Xiao, Hamed Laroui, Émilie Viennois, +8

Gastroenterology

NanoparticlesNanomedicineCross-protectionEngineeringNanobiotechnology +3

Mannosylated bioreducible nanoparticle-mediated macrophage-specific TNF-α RNA interference for IBD therapy

Bo Xiao, Hamed Laroui, Saravanan Ayyadurai, +4

Biomaterials

InflammationNanomedicineGene TherapiesIbd TherapyImmunology +5

Microbiota Modulate Host Gene Expression via MicroRNAs

Guillaume Dalmasso, Hang Thi Thu Nguyen, Yutao Yan, +5

PLoS ONE

Systems BiologyDysbiosisHost-microbe InteractionsImmunologyGerm-free Mice +12

Dextran sodium sulfate inhibits the activities of both polymerase and reverse transcriptase: lithium chloride purification, a rapid and efficient technique to purify RNA

Émilie Viennois, Fengyuan Chen, Hamed Laroui, +2

BMC Research Notes

Fab'-bearing siRNA TNFα-loaded nanoparticles targeted to colonic macrophages offer an effective therapy for experimental colitis

Hamed Laroui, Émilie Viennois, Bo Xiao, +4

Journal of Controlled Release

NanoparticlesNanomedicineInflammationDrug TargetingNanotherapeutics +11

Functional TNFα gene silencing mediated by polyethyleneimine/TNFα siRNA nanocomplexes in inflamed colon

Hamed Laroui, Arianne L. Theiss, Yutao Yan, +4

Biomaterials

InflammationMedicineImmunologyColorectal CancerPolyethyleneimine/tnfα Sirna Nanocomplexes +5

CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice

Hang Thi Thu Nguyen, Guillaume Dalmasso, Leif Törkvist, +8

Journal of Clinical Investigation

ImmunologyPathologyImmunologic MechanismInnate ImmunityImmunotherapy +15