Stanley van Herk

The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops

Sophie Ottema, Roger Mulet‐Lazaro, Claudia Erpelinck-Verschueren et al. · Nature Communications · 2021 · 78 citations · Full text

Medicine, Genetics, Oncology +17

Atypical 3q26/MECOM rearrangements genocopy inv(3)/t(3;3) in acute myeloid leukemia

Sophie Ottema, Roger Mulet‐Lazaro, H. Berna Beverloo et al. · Blood · 2020 · 76 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia

Leonie Smeenk, Sophie Ottema, Roger Mulet‐Lazaro et al. · Cancer Discovery · 2021 · 41 citations · Full text

Medicine, Genetics, Molecular Biology +17

Allele-specific expression of <i>GATA2</i> due to epigenetic dysregulation in <i>CEBPA</i> double-mutant AML

Roger Mulet‐Lazaro, Stanley van Herk, Claudia Erpelinck-Verschueren et al. · Blood · 2021 · 30 citations · Full text

Medicine, Genetics, Molecular Genetics +11

STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemia

Alexander Fischer, Benjamín Hernández-Rodríguez, Roger Mulet‐Lazaro et al. · Cell Reports · 2024 · 22 citations · Full text

Life Sciences, Genetics, Molecular Biology +17