Rebecca H. Graves

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

Alison E. John, Rebecca H. Graves, Kwok‐Tao Pun et al. · Nature Communications · 2020 · 117 citations · Full text

Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study

Anthony Cahn, Simon T. Hodgson, Robert C. Wilson et al. · BMC Pharmacology and Toxicology · 2013 · 52 citations · Full text

Asthma, Inflammatory Lung Disease, Lung Inflammation +19

Synthesis and Structure–Activity Relationships of Indazole Arylsulfonamides as Allosteric CC-Chemokine Receptor 4 (CCR4) Antagonists

Panayiotis A. Procopiou, John W. Barrett, Nicholas P. Barton et al. · Journal of Medicinal Chemistry · 2013 · 43 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Chemistry +17

Discovery of Novel Irreversible Inhibitors of Interleukin (IL)-2-inducible Tyrosine Kinase (Itk) by Targeting Cysteine 442 in the ATP Pocket

John D. Harling, Angela M. Deakin, Sébastien Campos et al. · Journal of Biological Chemistry · 2013 · 32 citations · Full text

Lead optimisation of the N1 substituent of a novel series of indazole arylsulfonamides as CCR4 antagonists and identification of a candidate for clinical investigation

Panayiotis A. Procopiou, Alison J. Ford, Rebecca H. Graves et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 20 citations · Full text

Medicinal Chemistry, Medicine, Indazole Arylsulfonamides +8