Role of phospholipase C, protein kinase C, and calcium in VEGF-induced venular hyperpermeability

H. Wu, Yuan Yuan, David C. Zawieja, +2

American Journal of Physiology-Heart and Circulatory Physiology

Autophagy-Lysosome Pathway in Renal Tubular Epithelial Cells Is Disrupted by Advanced Glycation End Products in Diabetic Nephropathy

Wei Jing Liu, Ting Ting Shen, Rui Hong Chen, +9

Journal of Biological Chemistry

SMAD3 promotes autophagy dysregulation by triggering lysosome depletion in tubular epithelial cells in diabetic nephropathy

Chen Yang, Xiaocui Chen, Zhihang Li, +7

Autophagy

Lysosome restoration to activate podocyte autophagy: a new therapeutic strategy for diabetic kidney disease

Wei Jing Liu, Yu Gan, Wei Fang Huang, +4

Cell Death and Disease

Urinary proteins induce lysosomal membrane permeabilization and lysosomal dysfunction in renal tubular epithelial cells

Wei Jing Liu, Bihua Xu, Lin Ye, +5

American Journal of Physiology-Renal Physiology

Renal PathologyRenal InflammationPathologyCytoskeletonNephrology +20

Blockage of the lysosome-dependent autophagic pathway contributes to complement membrane attack complex-induced podocyte injury in idiopathic membranous nephropathy

Wei Jing Liu, Zhihang Li, Xiaocui Chen, +7

Scientific Reports

MitophagyIdiopathic Membranous NephropathyImmunologyPathologyCell Death +20

Tyrosine phosphorylation of paxillin/pp125^FAKand microvascular endothelial barrier function

Yuan Yuan, Qiaobing Huang, James Hawker, +1

American Journal of Physiology-Heart and Circulatory Physiology

Metformin improves renal injury of MRL/lpr lupus-prone mice via the AMPK/STAT3 pathway

Xiaocui Chen, Dan Wu, H. Wu, +10

Lupus Science & Medicine

Macrophage autophagy protects against acute kidney injury by inhibiting renal inflammation through the degradation of TARM1

Xiao-Rong Huang, Ye Lin, Ning An, +15

Autophagy

Surfactant lipid peroxidation damages surfactant protein A and inhibits interactions with phospholipid vesicles

Alexander I. Kuzmenko, H. Wu, James P. Bridges, +1

Journal of Lipid Research

Proteinlipid InteractionPulmonary SurfactantEngineeringLipid PeroxidationInhibits Interactions +15