Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis

Xiao‐Ming Meng, Shuang Wang, Xiao-Ru Huang, +6

Cell Death and Disease

Inhibition of <i>METTL3</i> attenuates renal injury and inflammation by alleviating <i>TAB3</i> m6A modifications via IGF2BP2-dependent mechanisms

Jia-nan Wang, Fang Wang, Jing Ke, +20

Science Translational Medicine

TGF-β/Smad3 signalling regulates the transition of bone marrow-derived macrophages into myofibroblasts during tissue fibrosis

Shuang Wang, Xiao‐Ming Meng, Yee-Yung Ng, +13

Oncotarget

SMAD3 promotes autophagy dysregulation by triggering lysosome depletion in tubular epithelial cells in diabetic nephropathy

Chen Yang, Xiaocui Chen, Zhihang Li, +7

Autophagy

Chloroquine Autophagic Inhibition Rebalances Th17/Treg-Mediated Immunity and Ameliorates Systemic Lupus Erythematosus

Ning An, Yanwen Chen, Chao Wang, +6

Cellular Physiology and Biochemistry

Smad3 promotes AKI sensitivity in diabetic mice via interaction with p53 and induction of NOX4-dependent ROS production

Jianan Wang, Qin Yang, Chen Yang, +16

Redox Biology

Renal PathologyImmunologyRenal InflammationDiabetic MiceAki Sensitivity +25

Autophagy activation reduces renal tubular injury induced by urinary proteins

Wei Jing Liu, Mian-Na Luo, Jin Tan, +6

Autophagy

Autophagy ActivationAutophagic FluxRenal PathologyRenal InflammationCell Death +18

Therapeutic targeting of STAT3 with small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis

Min Tang, Chen Yang, Bingrui Li, +6

The FASEB Journal

Disturbance of mitochondrial dynamics and mitophagy in sepsis-induced acute kidney injury

Jian-xing Liu, Chen Yang, Weihuang Zhang, +4

Life Sciences

InflammationMitophagyMitochondrial FunctionMitochondrial DynamicMedicine +9

Basophil Activation-Dependent Autoantibody and Interleukin-17 Production Exacerbate Systemic Lupus Erythematosus

Qingjun Pan, Li Gong, Haiyan Xiao, +9

Frontiers in Immunology