Saad Alqarni

Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity

Zhengnan Shen, Kiira Ratia, Laura Cooper et al. · Journal of Medicinal Chemistry · 2021 · 205 citations · Full text

Molecular Docking, Medicine, Sars-cov-2 Plpro Inhibitors +13

Potent, Novel SARS-CoV-2 PLpro Inhibitors Block Viral Replication in Monkey and Human Cell Cultures

Zhengnan Shen, Kiira Ratia, Laura Cooper et al. · 2021 · 40 citations · Full text

Whereas Plpro, Human Cell Cultures, Viral Replication +14

Structural and free energy landscape analysis for the discovery of antiviral compounds targeting the cap-binding domain of influenza polymerase PB2

Amr S. Abouzied, Saad Alqarni, Kareem M. Younes et al. · Scientific Reports · 2024 · 32 citations · Full text

Synthesis, Optimization, and Structure–Activity Relationships of Imidazo[1,2-<i>a</i>]pyrimidines as Inhibitors of Group 2 Influenza A Viruses

Saad Alqarni, Laura Cooper, Jazmin Galván Achi et al. · Journal of Medicinal Chemistry · 2022 · 25 citations

A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts

Laura Bravo, Joana F F Simoes, Victor Roth Cardoso et al. · The Lancet Digital Health · 2024 · 14 citations · Full text