Martijn Kerkhofs

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease

Jeonghan Kim, Rajeev Gupta, Luz P. Blanco et al. · Science · 2019 · 677 citations · Full text

Mtdna Fragments, Vdac Oligomers, Molecular Biology +18

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics

Amado Carreras‐Sureda, Fabián Jaña, Hery Urra et al. · Nature Cell Biology · 2019 · 263 citations · Full text

Signal Transduction, Molecular Physiology, Mitochondrial Function +12

BIRD-2, a BH4-domain-targeting peptide of Bcl-2, provokes Bax/Bak-independent cell death in B-cell cancers through mitochondrial Ca2+-dependent mPTP opening

Martijn Kerkhofs, Rita La Rovere, Kirsten Welkenhuysen et al. · Cell Calcium · 2021 · 37 citations · Full text

Cancer Research, Bax/bak-independent Cell Death, Medicine +10

ABT‐199 (Venetoclax), a BH3‐mimetic Bcl‐2 inhibitor, does not cause Ca²⁺‐signalling dysregulation or toxicity in pancreatic acinar cells

Monika A. Jakubowska, Martijn Kerkhofs, Claudio Martines et al. · British Journal of Pharmacology · 2018 · 24 citations · Full text

The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions

Marine Lanfranchi, Sozerko Yandiev, Géraldine Meyer-Dilhet et al. · Nature Communications · 2024 · 22 citations · Full text