Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex

Eleonora Aronica, Frank Baas, Anand M. Iyer, +3

Neurobiology of Disease

Sporadic AlsNeurological DisorderNeurochemical BiomarkersDisease Gene IdentificationNeurology +15

Orexin-A represses satiety-inducing POMC neurons and contributes to obesity via stimulation of endocannabinoid signaling

Giovanna Morello, Roberta Imperatore, Letizia Palomba, +9

Proceedings of the National Academy of Sciences

Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor <scp>CB</scp>₁R signaling and anxiety‐like behavior

Roberta Imperatore, Giovanna Morello, Livio Luongo, +7

Journal of Neurochemistry

Anxiety‐like BehaviorGeneticsSynaptic SignalingCannabinoid PharmacologyEcb System +19

Cx26 partial loss causes accelerated presbycusis by redox imbalance and dysregulation of Nfr2 pathway

Anna Rita Fetoni, Veronica Zorzi, Fabiola Paciello, +20

Redox Biology

Negative Regulation of Leptin-induced Reactive Oxygen Species (ROS) Formation by Cannabinoid CB1 Receptor Activation in Hypothalamic Neurons

Letizia Palomba, Cristoforo Silvestri, Roberta Imperatore, +5

Journal of Biological Chemistry

Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signaling Deficiency

Luigia Cristino, Livio Luongo, Roberta Imperatore, +7

Neuropsychopharmacology

Pain SyndromeLeptin Signaling DeficiencyMolecular NeuroscienceMedicinePhysiology +11

Neuroinflammation and ALS: Transcriptomic Insights into Molecular Disease Mechanisms and Therapeutic Targets

Giovanna Morello, Antonio Gianmaria Spampinato, Sebastiano Cavallaro

Mediators of Inflammation

Sporadic AlsTranscriptomic InsightsNeuroinflammationNeurologyNeuropathology +16

Histamine Regulates the Inflammatory Profile of SOD1-G93A Microglia and the Histaminergic System Is Dysregulated in Amyotrophic Lateral Sclerosis

Savina Apolloni, Paola Fabbrizio, Susanna Amadio, +7

Frontiers in Immunology

Integrative multi-omic analysis identifies new drivers and pathways in molecularly distinct subtypes of ALS

Giovanna Morello, Maria Guarnaccia, Antonio Gianmaria Spampinato, +5

Scientific Reports

Deletion of Voltage-Dependent Anion Channel 1 knocks mitochondria down triggering metabolic rewiring in yeast

Andrea Magrì, Maria Carmela Di Rosa, Ivan Orlandi, +9

Cellular and Molecular Life Sciences

Signal TransductionMitochondrial FunctionBiochemistryMitochondrial DynamicPhysiology +7