Novel antigen-presenting cell imparts Treg-dependent tolerance to gut microbiota

Blossom Akagbosu, Zakieh Tayyebi, Gayathri Shibu, +20

Nature

Gene editing to induce FOXP3 expression in human CD4 ⁺ T cells leads to a stable regulatory phenotype and function

Yuchi Honaker, Nicholas Hubbard, Yufei Xiang, +14

Science Translational Medicine

Emergency Whole-Blood Use in the Field

Geir Strandenes, Marc De Pasquale, P. Andrew, +9

Shock

Mycobacterium tuberculosis Induces Irg1 in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis

Caio César Barbosa Bomfim, Logan Fisher, Eduardo P. Amaral, +12

Frontiers in Cellular and Infection Microbiology

BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility

Eduardo P. Amaral, Sivaranjani Namasivayam, Artur T. L. Queiroz, +23

Nature Microbiology

Heme oxygenase-1 inhibition promotes IFNγ- and NOS2-mediated control of Mycobacterium tuberculosis infection

Diego L. Costa, Eduardo P. Amaral, Sivaranjani Namasivayam, +7

Mucosal Immunology

A wave of Thetis cells imparts tolerance to food antigens early in life

Vanja Cabric, Yollanda Edwirges Moreira Franco, Tyler Park, +8

Science

Thetis cells induce food-specific Treg cell differentiation and oral tolerance

Yollanda Edwirges Moreira Franco, Vanja Cabric, Tyler Park, +8