Yakov Chudnovsky

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance

Do‐Hoon Kim, Brian P. Fiske, Kıvanç Birsoy et al. · Nature · 2015 · 376 citations · Full text

Medicine, Cell Biology, Oncology +6

Comprehensive Genomic Profiling of 282 Pediatric Low- and High-Grade Gliomas Reveals Genomic Drivers, Tumor Mutational Burden, and Hypermutation Signatures

Adrienne Johnson, Eric A. Severson, Laurie M. Gay et al. · The Oncologist · 2017 · 289 citations · Full text

Medicine, Genetics, Oncology +17

Use of human tissue to assess the oncogenic activity of melanoma-associated mutations

Yakov Chudnovsky, Amy E. Adams, Paul B. Robbins et al. · Nature Genetics · 2005 · 198 citations · Full text

Medicine, Genetics, Oncology +16

Menin Inhibition With Revumenib for <i>KMT2A</i> -Rearranged Relapsed or Refractory Acute Leukemia (AUGMENT-101)

Ghayas C. Issa, Ibrahim Aldoss, Michael J. Thirman et al. · Journal of Clinical Oncology · 2024 · 184 citations · Full text

Medicine, Oncology, Pharmacology +12

ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State

Yakov Chudnovsky, Do‐Hoon Kim, Siyuan Zheng et al. · Cell Reports · 2014 · 144 citations · Full text

Medicine, Cancer Biology, Oncology +17