Association of Circulating Sex Hormones With Inflammation and Disease Severity in Patients With COVID-19

Sandeep Dhindsa, Nan Zhang, Michael J. McPhaul, +8

JAMA Network Open

Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity

Nan Zhang, Rafael S. Czepielewski, Nicholas N. Jarjour, +10

The Journal of Experimental Medicine

Microbial PathogensFactor VInnate Immune SystemImmunologyResident Macrophages +19

LYVE1+ macrophages of murine peritoneal mesothelium promote omentum-independent ovarian tumor growth

Nan Zhang, Seung Hyeon Kim, Anastasiia Gainullina, +14

The Journal of Experimental Medicine

Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor

Rafael S. Czepielewski, Emma Erlich, Emily J. Onufer, +13

Immunity

InflammationLymphatic ValvesMesenteric Lymph FlowAutoimmune DiseaseMucosal Immunology +8

AVX-470, an Orally Delivered Anti-Tumour Necrosis Factor Antibody for Treatment of Active Ulcerative Colitis: Results of a First-in-Human Trial

M. Scott Harris, Hartman Deborah, Brenda Lemos, +7

Journal of Crohn s and Colitis

AVX-470

Kailash C. Bhol, Daniel E. Tracey, Brenda Lemos, +8

Inflammatory Bowel Diseases

Effects of AVX-470, an Oral, Locally Acting Anti-Tumour Necrosis Factor Antibody, on Tissue Biomarkers in Patients with Active Ulcerative Colitis

Deborah Hartman, Daniel E. Tracey, Brenda Lemos, +8

Journal of Crohn s and Colitis

Human serous cavity macrophages and dendritic cells possess counterparts in the mouse with a distinct distribution between species

Jichang Han, Alexandre Gallerand, Emma Erlich, +18

Nature Immunology

Macrophage BiologyInflammationGranulocyteImmunologyPathology +7

Peripheral blood mononuclear cell tissue factor (F3 gene) transcript levels and circulating extracellular vesicles are elevated in severe coronavirus 2019 (COVID-19) disease

Thomas Girard, Lilian Antunes, Nan Zhang, +10

Journal of Thrombosis and Haemostasis

Extracellular VesiclesSevere Coronavirus 2019PathogenesisImmunologyViral Pathogenesis +6

Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis

Pablo Canales-Herrerías, Mathieu Uzzan, Akihiro Seki, +42

Science Immunology