Robert A. Mack

The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist

John E. Macor, David Gurley, Thomas H. Lanthorn et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 157 citations · Full text

(−)-Spiro[1-azabicyclo[2.2.2]octane-3,5‘-oxazolidin-2‘-one], a Conformationally Restricted Analogue of Acetylcholine, Is a Highly Selective Full Agonist at the α7 Nicotinic Acetylcholine Receptor

G. B. MULLEN, James Napier, Michael Balestra et al. · Journal of Medicinal Chemistry · 2000 · 132 citations · Full text

Pharmacotherapy, Social Sciences, Molecular Pharmacology +19

Synthesis and Use of 5-Vinyl-1,2,4-oxadiazoles as Michael Acceptors. A Rapid Synthesis of the Potent Muscarinic Agonist L-670,548

John E. Macor, Timothy Ordway, Robert L. Smith et al. · The Journal of Organic Chemistry · 1996 · 48 citations

Molecular Pharmacology, Medicinal Chemistry, A Rapid Synthesis +15

Drug-induced modifications of the immune response. 12. 4,5-Dihydro-4-oxo-2-(substituted amino)-3-furancarboxylic acids and derivatives as novel antiallergic agents

Robert A. Mack, W. ZAZULAK, Lesley A. Radov et al. · Journal of Medicinal Chemistry · 1988 · 46 citations

Inflammation, Medicinal Chemistry, Pharmaceutical Chemistry +14

A Chiral Synthesis of (−)-Spiro[1-azabicyclo[2.2.2]octane-3,5‘- oxazolidin-2‘-one]:  A Conformationally Restricted Analogue of Acetylcholine That Is a Potent and Selective α7 Nicotinic Receptor Agonist

John E. Macor, G. B. MULLEN, Patrick R. Verhoest et al. · The Journal of Organic Chemistry · 2004 · 28 citations

Molecular Pharmacology, Pharmaceutical Chemistry, Biochemistry +13