LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer

Tara Boulding, Robert McCuaig, A. Tan, +14

Scientific Reports

Genome-Wide Analysis of Gene Expression in T Cells to Identify Targets of the NF-κB Transcription Factor c-Rel

Karen Bunting, Sudha Rao, Kristine Hardy, +5

The Journal of Immunology

Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer

Abel Tan, W. Tu, Robert McCuaig, +5

Frontiers in Immunology

Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer

Tara Boulding, Fan Wu, Robert McCuaig, +8

PLoS ONE

Breast OncologyDifferential RolesCancer BiologyTumor BiologyTranscriptional Regulation +21

The NF-κB Transcription Factor c-Rel Is Required for Th17 Effector Cell Development in Experimental Autoimmune Encephalomyelitis

Guobing Chen, Kristine Hardy, Eloisa Pagler, +5

The Journal of Immunology

Regulation of the IL-21 Gene by the NF-κB Transcription Factor c-Rel

Guobing Chen, Kristine Hardy, Karen Bunting, +3

The Journal of Immunology

Lymphocyte DevelopmentT-regulatory CellImmunologyImmune RegulationImmunologic Mechanism +20

Transcriptional Networks and Cellular Senescence in Human Mammary Fibroblasts

Kristine Hardy, L. Mansfield, Alan Mackay, +5

Molecular Biology of the Cell

Systems BiologyMammary GlandGene RegulationCoordinated SenescenceCancer Genomics +11

Excitotoxic Cell Death Dependent on Inhibitory Receptor Activation

Quan Chen, Krista L. Moulder, Tatiana Tenkova, +3

Experimental Neurology

MedicineApoptosisImmunologyCell DeathNeuropharmacology +4

Dichloroacetate Prevents Cisplatin-Induced Nephrotoxicity without Compromising Cisplatin Anticancer Properties

Ramindhu Galgamuwa, Kristine Hardy, Jane E. Dahlstrom, +11

Journal of the American Society of Nephrology

Cisplatin UseUrologyRenal FunctionMitochondrial DysfunctionMedicine +9

Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch

Wen Juan Tu, Robert McCuaig, Abel Tan, +14

Frontiers in Immunology