Matthew Mannarino

Senotherapeutic drugs for human intervertebral disc degeneration and low back pain

Hosni Cherif, Daniel G. Bisson, Matthew Mannarino et al. · eLife · 2020 · 119 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Single-Cell RNA-Seq Analysis of Cells from Degenerating and Non-Degenerating Intervertebral Discs from the Same Individual Reveals New Biomarkers for Intervertebral Disc Degeneration

Hosni Cherif, Matthew Mannarino, Alain Pacis et al. · International Journal of Molecular Sciences · 2022 · 96 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin

Matthew Mannarino, Hosni Cherif, Li Li et al. · Arthritis Research & Therapy · 2021 · 46 citations · Full text

Life Sciences, Immunology, Orthopaedic Surgery +16

Senolytic treatment for low back pain

Matthew Mannarino, Hosni Cherif, Saber Ghazizadeh Darband et al. · Science Advances · 2025 · 27 citations · Full text

Medicine, Neuroscience, Orthopaedic Surgery +13

Senolytic Combination Treatment Is More Potent Than Single Drugs in Reducing Inflammatory and Senescence Burden in Cells from Painful Degenerating IVDs

Matthew Mannarino, Oliver Wu-Martinez, Kai Sheng et al. · Biomolecules · 2023 · 25 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14