Concepedia

Publication | Open Access

Senolytic Combination Treatment Is More Potent Than Single Drugs in Reducing Inflammatory and Senescence Burden in Cells from Painful Degenerating IVDs

DOIFull Paper Access

23

Citations

25

References

2023

Year

Matthew Mannarino, Oliver Wu-Martinez, Kai Sheng, Li Li, Rodrigo Navarro-Ramírez, Peter Jarzem, Jean Ouellet, Hosni Cherif, Lisbet Haglund
Biomolecules

Abstract

Combining o-Vanillin and RG-7112 greatly enhanced the effect of either senolytic alone. Together, these results support the potential of senolytics as a promising treatment for IVD-related low back pain.

References

YearCitations

Page 1