Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9

Mathilde Mathieu, Nathalie Névo, Mabel Jouve, +11

Nature Communications

Spatial Positioning and Matrix Programs of Cancer-Associated Fibroblasts Promote T-cell Exclusion in Human Lung Tumors

John A. Grout, Philémon Sirven, Andrew M. Leader, +36

Cancer Discovery

Different TCR-induced T lymphocyte responses are potentiated by stiffness with variable sensitivity

Michael Saitakis, Stéphanie Dogniaux, Christel Goudot, +6

eLife

The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus

Matteo Gentili, Xavier Lahaye, Francesca Nadalin, +14

Cell Reports

Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion

Guilherme Pedreira de Freitas Nader, Sonia Agüera‐González, Fiona Routet, +20

Cell

ChromatinGenome InstabilityMedicineDna ReplicationCancer Cell Biology +8

Innate control of actin nucleation determines two distinct migration behaviours in dendritic cells

Pablo Vargas, Paolo Maiuri, Marine Bretou, +18

Nature Cell Biology

Signal TransductionCell InteractionCell TraffickingDendritic CellsCell Migration +9

Toll-like Receptor 4 Engagement on Dendritic Cells Restrains Phago-Lysosome Fusion and Promotes Cross-Presentation of Antigens

Andrés Alloatti, Fiorella Kotsias, Anne-Marie Pauwels, +15

Immunity

InflammationToll-like ReceptorsMedicineInnate Immune SystemImmunology +6

Human Primary Immune Cells Exhibit Distinct Mechanical Properties that Are Modified by Inflammation

Nathalie Bufi, Michael Saitakis, Stéphanie Dogniaux, +6

Biophysical Journal

InflammationCytokineInflammatory DiseaseAutoimmune DiseaseAre Modified +8

HLA-independent T cell receptors for targeting tumors with low antigen density

Jorge Mansilla‐Soto, Justin Eyquem, Sascha Haubner, +22

Nature Medicine

Cancer ImmunosurveillanceT-regulatory CellImmunologyTumor ImmunityAntigen Processing +7

Lysosome signaling controls the migration of dendritic cells

Marine Bretou, Pablo J. Sáez, Doriane Sanséau, +13

Science Immunology