Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut

Michael R. Howitt, Sydney Lavoie, Monia Michaud, +9

Science

Microbial PathogensInnate Immune SystemImmunologyTuft CellsGut Microbiota +15

Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

Dror S. Shouval, Amlan Biswas, Jeremy A. Goettel, +26

Immunity

InflammationCytokineAutoimmune DiseaseMucosal ImmunologyInnate Immune System +10

CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function

Eunyoung Chun, Sydney Lavoie, Monia Michaud, +6

Cell Reports

Tumor BiologyColonic MdscsCancer ImmunosurveillanceCcl2 NeutralizationMedicine +10

Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity

Eunyoung Chun, Sydney Lavoie, Diogo Fonseca‐Pereira, +9

Immunity

InflammationGut ImmunityMucosal ImmunologyInnate Lymphoid CellsImmunology +8

The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response

Sydney Lavoie, Kara L. Conway, Kara G. Lassen, +13

eLife

<i>Fusobacterium nucleatum</i> drives a pro-inflammatory intestinal microenvironment through metabolite receptor-dependent modulation of IL-17 expression

Caitlin A. Brennan, Slater L. Clay, Sydney Lavoie, +7

Gut Microbes

Expression of Free Fatty Acid Receptor 2 by Dendritic Cells Prevents Their Expression of Interleukin 27 and Is Required for Maintenance of Mucosal Barrier and Immune Response Against Colorectal Tumors in Mice

Sydney Lavoie, Eunyoung Chun, Sena Bae, +10

Gastroenterology

InflammationCytokineMucosal ImmunologyDendritic Cells PreventsImmunology +9

QseC inhibition as an antivirulence approach for colitis-associated bacteria

Michelle Rooks, Patrick Veiga, Analise Z. Reeves, +12

Proceedings of the National Academy of Sciences

Regulatory proteins for the activated third and fourth components of complement (C3b and C4b) in mice. II. Identification and properties of complement receptor type 1 (CR1).

Taroh Kinoshita, Sydney Lavoie, Victor Nussenzweig

The Journal of Immunology