Barry Crook

GSK189254, a Novel H3 Receptor Antagonist That Binds to Histamine H3 Receptors in Alzheimer’s Disease Brain and Improves Cognitive Performance in Preclinical Models

Andrew D. Medhurst, A.R. Atkins, I.J.M. Beresford et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 301 citations

Medicine, Medicinal Chemistry, Pharmacology +13

LPA1 receptor-deficient mice have phenotypic changes observed in psychiatric disease

Stephen Harrison, Charlie Reavill, Gerald L. Brown et al. · Molecular and Cellular Neuroscience · 2003 · 127 citations

Medicine, Molecular Genetics, Psychiatry +7

The PPARγ agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B

Leann P. Quinn, Barry Crook, Mark Hows et al. · British Journal of Pharmacology · 2008 · 119 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

TRPM2 Is Elevated in the tMCAO Stroke Model, Transcriptionally Regulated, and Functionally Expressed in C13 Microglia

Elena Fonfría, César Mattei, Kerstin Hill et al. · Journal of Receptors and Signal Transduction · 2006 · 81 citations

Life Sciences, Neurobiology, Neuroscience +17

Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats

Andrew D. Medhurst, Michael A. Briggs, Gordon Bruton et al. · Biochemical Pharmacology · 2007 · 64 citations

Life Sciences, Neuroscience, Pharmacology +12