Concepedia

Glenn Spehar

GS

Statistics

Publications

7

Citations

1.4K

H-Index

7

Active since

2006

Affiliations

GlaxoSmithKline (United States)(Current)

Research Triangle Park Foundation

Glenn Spehar is an author at GlaxoSmithKline (United States) specializing in medicine, pharmacology, and drug discovery.

Top concepts

Publications per year

2006–2009

7

Publications

7

Activity of the Dual Kinase Inhibitor Lapatinib (GW572016) against HER-2-Overexpressing and Trastuzumab-Treated Breast Cancer Cells

Gottfried E. Konecny, Mark D. Pegram, Natarajan Venkatesan et al. · Cancer Research · 2006 · 904 citations

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Assessment of epidermal growth factor receptor (EGFR, ErbB1) and HER2 (ErbB2) protein expression levels and response to lapatinib (Tykerb<sup>®</sup>, GW572016) in an expanded panel of human normal and tumour cell lines

David W. Rusnak, Krystal J. Alligood, Robert J. Mullin et al. · Cell Proliferation · 2007 · 174 citations · Full text

<i>In vitro</i> biological activity of a novel small-molecule inhibitor of polo-like kinase 1

Timothy J. Lansing, Randy T. McConnell, Derek R. Duckett et al. · Molecular Cancer Therapeutics · 2007 · 139 citations · Full text

Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors

Tara Rheault, Thomas R. Caferro, Scott H. Dickerson et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 83 citations · Full text

, , +5

Impact of Common Epidermal Growth Factor Receptor and HER2 Variants on Receptor Activity and Inhibition by Lapatinib

Tona M. Gilmer, LouAnn Cable, Krystal J. Alligood et al. · Cancer Research · 2008 · 70 citations · Full text

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