Ian Rowles

Engineering an Enantioselective Amine Oxidase for the Synthesis of Pharmaceutical Building Blocks and Alkaloid Natural Products

Diego Ghislieri, Anthony P. Green, Marta Pontini et al. · Journal of the American Chemical Society · 2013 · 363 citations

Combinatorial Chemistry, Engineering, Organic Chemistry +18

Directed Evolution of the Enzyme Monoamine Oxidase (MAO‐N): Highly Efficient Chemo‐enzymatic Deracemisation of the Alkaloid (±)‐Crispine A

Ian Rowles, Kirk J. Malone, Laura L. Etchells et al. · ChemCatChem · 2012 · 65 citations

An Engineered Cytidine Deaminase for Biocatalytic Production of a Key Intermediate of the Covid-19 Antiviral Molnupiravir

Ashleigh J. Burke, William R. Birmingham, Ying Zhuo et al. · Journal of the American Chemical Society · 2022 · 48 citations · Full text

Engineering of phenylalanine ammonia lyase from Rhodotorula graminis for the enhanced synthesis of unnatural l-amino acids

Ian Rowles, Bas Groenendaal, Barış Bi̇nay et al. · Tetrahedron · 2016 · 46 citations

Biomanufacturing, Biosynthesis, Engineering +12

Deracemisation of benzylisoquinoline alkaloids employing monoamine oxidase variants

Joerg H. Schrittwieser, Bas Groenendaal, Simon C. Willies et al. · Catalysis Science & Technology · 2014 · 26 citations

Mao-n Variant D11, Biochemistry, Medicine +9