Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Merryn Voysey, Sue Ann Costa Clemens, Shabir A. Madhi, +758

The Lancet

Benzothiazinones Kill <i>Mycobacterium tuberculosis</i> by Blocking Arabinan Synthesis

Vadim Makarov, Giulia Manina, Katarı́na Mikus̃ová, +34

Science

Bioorganic ChemistryMajor Btz TargetAntimicrobial ChemotherapyPharmaceutical ChemistryDrug Resistance +16

Extremely potent human monoclonal antibodies from COVID-19 convalescent patients

Emanuele Andreano, Emanuele Nicastri, Ida Paciello, +32

Cell

ImmunologyAntibody ScreeningAntibody EngineeringImmunotherapyMedicine +2

Towards a new tuberculosis drug: pyridomycin – nature's isoniazid

Ruben C. Hartkoorn, Claudia Sala, João Neres, +7

EMBO Molecular Medicine

Lansoprazole is an antituberculous prodrug targeting cytochrome bc1

Jan Rybniker, Anthony Vocat, Claudia Sala, +4

Nature Communications

Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants

Emanuele Andreano, Ida Paciello, Giulia Piccini, +16

Nature

The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis

Luis Solans, Jesús Gonzalo‐Asensio, Claudia Sala, +7

PLoS Pathogens

EngineeringMolecular BiologyTranscriptional RegulationMycobacterium TuberculosisPhop-dependent Ncrna Mcr7 +17

Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein

Benjamin Blasco, Jeffrey M. Chen, Ruben C. Hartkoorn, +5

PLoS Pathogens

Virulence Regulator EsprMolecular BiologyMedical MicrobiologyTranscriptional RegulationProtein Expression +19

Simple Model for Testing Drugs against Nonreplicating <i>Mycobacterium tuberculosis</i>

Claudia Sala, Neeraj Dhar, Ruben C. Hartkoorn, +4

Antimicrobial Agents and Chemotherapy

Simple ModelAntibiotic AdjuvantTuberculosis PreventionImmunologyDiagnostics +19

Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence Protein Secretion

Jan Rybniker, Jeffrey M. Chen, Claudia Sala, +12

Cell Host & Microbe

Health SciencesVirulence FactorTuberculosisMicrobiologyMedicine +3