The X-ray Crystal Structure of Full-Length Human Plasminogen

Ruby H. P. Law, Tom T. Caradoc-Davies, Nathan Cowieson, +11

Cell Reports

Tranexamic acid is an active site inhibitor of urokinase plasminogen activator

Guojie Wu, Blake A. Mazzitelli, Adam J. Quek, +8

Blood Advances

Active Site InhibitorPathologyActive-site InhibitorCancer BiologyTumor Biology +16

X-ray crystal structure of plasmin with tranexamic acid–derived active site inhibitors

Ruby H. P. Law, Guojie Wu, Eleanor W. W. Leung, +9

Blood Advances

A mechanism for hereditary angioedema caused by a lysine 311–to–glutamic acid substitution in plasminogen

S. Kent Dickeson, Sunil Kumar, Mao-fu Sun, +7

Blood

Gas‐Generating, pH‐Responsive Calcium Carbonate Hybrid Particles with Biomimetic Coating for Contrast‐Enhanced Ultrasound Imaging

Mark Louis P. Vidallon, Alon M. Douek, Adam J. Quek, +5

Particle & Particle Systems Characterization

NanoparticlesBiomedical AcousticsNanotherapeuticsEngineeringBiofabrication +22

Dimerization Is Not a Determining Factor for Functional High Affinity Human Plasminogen Binding by the Group A Streptococcal Virulence Factor PAM and Is Mediated by Specific Residues within the PAM a1a2 Domain

Sarbani Bhattacharya, Zhong Liang, Adam J. Quek, +3

Journal of Biological Chemistry

Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding

Adam J. Quek, Blake A. Mazzitelli, Guojie Wu, +11

Journal of Molecular Biology

BiochemistryStructural BioinformaticsProtein FoldingMedicineNatural Sciences +10

Polynorepinephrine as an Efficient Antifouling-Coating Material and Its Application as a Bacterial Killing Photothermal Agent

Zhenzhen Lu, Adam J. Quek, Shane P. Meaney, +3

ACS Applied Bio Materials

Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes

Yue Yuan, Yetunde A. Ayinuola, Damini Singh, +8

Journal of Structural Biology

Protein AssemblyBiochemistryNatural SciencesHuman PlasminogenBiomolecular Structure Prediction +8

Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface

Milena M. Awad, M. Hutton, Adam J. Quek, +19

Gastroenterology

Microbial ToxinSpore SurfaceMedical MicrobiologyMicrobial DiseasePathogen Transmission +9