RcsCDB His‐Asp phosphorelay system negatively regulates the <i>flhDC</i> operon in <i>Escherichia coli</i>

Anne Francez‐Charlot, Bruno Laugel, Alice Van Gemert, +5

Molecular Microbiology

BiosynthesisBiochemistryOperon FlhdcNatural SciencesGenetics +13

Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

Angel Varela‐Rohena, Peter Molloy, Steven M. Dunn, +16

Nature Medicine

Hiv-1 Immune EscapeAutoimmune DiseaseCd8 T CellsT-regulatory CellHuman Retrovirus +9

Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties

Bruno Laugel, Hugo A. van den Berg, Emma Gostick, +5

Journal of Biological Chemistry

Tetramer Binding PropertiesAutoimmune DiseaseAllergyAdaptive Immune SystemT Cells +13

Interaction between the CD8 Coreceptor and Major Histocompatibility Complex Class I Stabilizes T Cell Receptor-Antigen Complexes at the Cell Surface

Linda Wooldridge, Hugo A. van den Berg, Meir Glick, +7

Journal of Biological Chemistry

T-regulatory CellImmunologyImmunologic MechanismAntigen ProcessingCd4 T Cell Responses +15

Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens

Erin W. Meermeier, Bruno Laugel, Andrew K. Sewell, +7

Nature Communications

The CD8 T Cell Coreceptor Exhibits Disproportionate Biological Activity at Extremely Low Binding Affinities

Sarah Hutchinson, Linda Wooldridge, Sabrina Tafuro, +6

Journal of Biological Chemistry

CD8 Controls T Cell Cross-Reactivity

Linda Wooldridge, Bruno Laugel, Julia Ekeruche, +4

The Journal of Immunology

Autoimmune DiseaseAllergyPmhci AgsT CellsT-regulatory Cell +11

Adenosine and <scp>cAMP</scp> signalling skew human dendritic cell differentiation towards a tolerogenic phenotype with defective CD8⁺ T‐cell priming capacity

John Challier, Denis Bruniquel, Andrew K. Sewell, +1

Immunology

Adenosine Hampers Cd8Adenosine ReceptorsImmune RegulationImmunologyPathology +20

Design of Soluble Recombinant T Cell Receptors for Antigen Targeting and T Cell Inhibition

Bruno Laugel, Jonathan M. Boulter, Nikolai M. Lissin, +9

Journal of Biological Chemistry

Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region

Linda Wooldridge, Anna Lissina, Jonathan Vernazza, +11

European Journal of Immunology