Frank E. Kwarcinski

The tethered peptide activation mechanism of adhesion GPCRs

Ximena Barros-Álvarez, Robert M. Nwokonko, Alexander Vizurraga et al. · Nature · 2022 · 152 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Conformation-Selective Analogues of Dasatinib Reveal Insight into Kinase Inhibitor Binding and Selectivity

Frank E. Kwarcinski, Kristoffer Brandvold, Sameer Phadke et al. · ACS Chemical Biology · 2016 · 73 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Irreversible Inhibitors of c-Src Kinase That Target a Nonconserved Cysteine

Frank E. Kwarcinski, Christel C. Fox, Michael E. Steffey et al. · ACS Chemical Biology · 2012 · 45 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +15

A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation

Alfredo Picado, A. Chaikuad, Carrow I. Wells et al. · Journal of Medicinal Chemistry · 2020 · 30 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +13

UM-164: A Potent c-Src/p38 Kinase Inhibitor with <i>In Vivo</i> Activity against Triple-Negative Breast Cancer

Rabia A. Gilani, Sameer Phadke, Li Bao et al. · Clinical Cancer Research · 2016 · 27 citations

Medicine, Oncology, Pharmacology +17