Mark Rolfe

Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2)

Mark Rolfe, Laura E. McLeod, Phillip F. Pratt et al. · Biochemical Journal · 2005 · 125 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +16

The human UNP locus at 3p21.31 encodes two tissue-selective, cytoplasmic isoforms with deubiquitinating activity that have reduced expression in small cell lung carcinoma cell lines

Amy Frederick, Mark Rolfe, M. Isabel Chiu · Oncogene · 1998 · 50 citations

Medicine, Genetics, Molecular Genetics +10

Pharmacological and Genetic Evaluation of Proposed Roles of Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase (MEK), Extracellular Signal-regulated Kinase (ERK), and p90RSK in the Control of mTORC1 Protein Signaling by Phorbol Esters

Bruno D. Fonseca, Tommy Alain, Leona K. Finestone et al. · Journal of Biological Chemistry · 2011 · 45 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Early indicators of disease progression in Fabry disease that may indicate the need for disease-specific treatment initiation: findings from the opinion-based PREDICT-FD modified Delphi consensus initiative

Derralynn Hughes, Patrício Aguiar, Patrick Deegan et al. · BMJ Open · 2020 · 38 citations · Full text

Medicine, Nephrology, Neurology +13

Ca2+-independent protein kinase C activity is required for alpha1-adrenergic-receptor-mediated regulation of ribosomal protein S6 kinases in adult cardiomyocytes

Lijun Wang, Mark Rolfe, Christopher G. Proud · Biochemical Journal · 2003 · 36 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16