X Chen

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein.

Jill Bargonetti, James J. Manfredi, X Chen et al. · Genes & Development · 1993 · 267 citations · Full text

Two yeast genes with similarity to TCP-1 are required for microtubule and actin function in vivo.

X Chen, Donald Sullivan, Tim C. Huffaker · Proceedings of the National Academy of Sciences · 1994 · 127 citations · Full text

Tcp-1 Family, Molecular Biology, Cytoskeleton +17

Cooperative DNA binding of p53 with TFIID (TBP): a possible mechanism for transcriptional activation.

X Chen, George E. Farmer, Hua Zhu et al. · Genes & Development · 1993 · 126 citations · Full text

Molecular Regulation, Molecular Biology, Gene Regulatory Network +20

Harnessing the cross-talk between tumor cells and tumor-associated macrophages with a nano-drug for modulation of glioblastoma immune microenvironment

Tong‐Fei Li, Ke Li, Chao Wang et al. · Journal of Controlled Release · 2017 · 90 citations

Nanomedicine, Tumor-associated Macrophages, Glioma +10

Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth

Da Ma, X Chen, P-Y Zhang et al. · Oncogene · 2017 · 64 citations

Dietary Restriction Suppresses, Oncology, Chemoprevention Strategy +11